The Cell Danger Response is how cells, once injured, infected or poisoned, return to health. It is an evolutionarily conserved, three step process that has it’s roots in single-celled life 3.5 billions of years old.
Understanding the Cell Danger Response is not required in order to go through the 4 Stage Process outlined in the Signature Program, which provides you with the core formulas, practices and strategy for understanding how to interpret your outputs, course correct and confidently know how to support yourself towards greater health.
However when it comes to understanding lab work, our counts of various proteins, minerals, and cell types, at this point in time I don’t believe you can understand what any of that means without understanding how the Cell Danger Response works and what happens to our cells in each step of healing.
The material below is centered around answering a question: why don’t I usually recommend any specific adaptations to the program based on lab results, such as low or elevated hormones?
- How can we use the same process for a variety of lab results and get exceptional outcomes?
- Looking at examples of low and high hormones on the Dutch Test
- The therapeutic process is the same; the execution and specifics are individual
- Understanding the Levels of Organization of complex life
- Intro into the Cell Danger Response
- How cells behave when they’re healthy
- Mitochondria dynamically change shape and function between “spaghetti” and “meatballs”
- Healthy mitochondria shift dynamically according to daily and seasonal rhythms
- Triggers of the CDR
- Factors that influence which symptoms you have
- The CDR has 3 distinct stages with distinct metabolism and checkpoints
- Healing Step 1 - CDR 1 - the Innate Immune System
- Healing Step 2 - CDR 2 - the Adaptive Immunity
- Healing Step 3 - CDR 3 - Memory and reconnection
- The evolution of the immune system and identity
- Key features of each Step - Chart
- Communication between mitochondria and you
- Our biochemistry is downstream of these health and healing cycles
- Local issues need to be communicated up to to you
- When cells shift into the CDR, they need to separate from the network in order to heal
- The CDR and the 4 Stage Approach to healing
- The problem with trying to address hormones levels directly
- Comparing low and high hormone levels and the helpfulness of an ecological approach
- Most modern health problems are ecological in nature, not primarily microscopic
Key papers about the Cell Danger Response
- Metabolic Features of the Cell Danger Response (2014)
- Perspective: Cell danger response Biology—The new science that connects environmental health with mitochondria and the rising tide of chronic illness (2019)
- Incomplete Healing as a Cause of Aging: The Role of Mitochondria and the Cell Danger Response (2019)